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Seebio Biotech (Shanghai) Co., Ltd.
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Dextran is a complex branched glucan (polysaccharide derived from the condensation of glucose. IUPAC defines dextrans as "Branched poly-α-d-glucosides of microbial origin having glycosidic bonds predominantly C-1 → C-6".[1] Dextran chains are of varying lengths (from 3 to 2000 kilodaltons).
The polymer main chain consists of α-1,6 glycosidic linkages between glucose monomers, with branches from α-1,3 linkages. This characteristic branching distinguishes a dextran from a dextrin, which is a straight chain glucose polymer tethered by α-1,4 or α-1,6 linkages.
Function
An uncommon but significant complication of dextran osmotic effect is acute renal failure. The pathogenesis of this renal failure is the subject of many debates with direct toxic effect on tubules and glomerulus versus intraluminal hyperviscosity being some of the proposed mechanisms. Patients with history of diabetes mellitus, renal insufficiency, or vascular disorders are most at risk. Brooks and others recommend the avoidance of dextran therapy in patients with chronic renal insufficiency.
Application
Medicinally it is used as an antithrombotic (antiplatelet), to reduce blood viscosity, and as a volume expander in hypovolaemia. Dextran 70 is on the WHO Model List of Essential Medicines, the most important medications needed in a health system.
1, It is used in some eye drops as a lubricant.[9] and in certain intravenous fluids to solubilize other factors, such as iron (in a solution known as Iron Dextran).
2, Intravenous solutions with dextran function both as volume expanders and means of parenteral nutrition. Such a solution provides an osmotically neutral fluid that once in the body is digested by cells into glucose and free water. It is occasionally used to replace lost blood in emergency situations, when replacement blood is not available, but must be used with caution as it does not provide necessary electrolytes and can cause hyponatremia or other electrolytedisturbances.
3, It also increases blood sugar levels.
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Seebio Biotech (Shanghai) Co., Ltd.
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Diosgenin industrial grade,medicine grade CAS Number 512-04-9 Molecular Formula C27H42O3 Molecular Weight 414.6206 Package：25kg/barrel Function: hormone intermediates Application: hormone drugs Tags: New Products Anti Bacterial.
Diosgenin is the important basic raw material of steroid hormone drugs. Steroid hormone has strong pharmacological effects of anti-infection, anti-allergic, anti-virus and anti-shock, it is important medicine to treat rheumatism, cardiovascular, lymphatic leukemia, cell encephalitis, skin diseases and tumor and to save critical patients; It is raw material of acetate dehydropregnenolone which is the important intermediates of steroid hormone drugs and through it all kinds of steroid drugs can be synthesized, such as hydrocortisone, prednisone, norethindrone, fluocinolone, dexamethasone and so on.
Diosgenin is called medicinal gold in pharmaceutical industry, the medicinal value is very high and the uses are broad. Chinese Diosgenin is steady growing basic materials of hormone in the world, Chinahas been in dominant and monopolistic position. The diosgenin extracted from turmeric is important basic raw material in pharmaceutical industry to synthesize hormone, it can be used in synthesis of intermediates including dienes and 16，17-a-Epoxyprogesterone , it’s also the starting material of bulk drug hormone, such as progestin, prednisone acetate, budesonide, methyl testosteron.
Complied to Ministerial level standard
Melting point≥195℃
Properties: white or slight yellow crystalline powder, no obvious oil lost taste or other strange smell.
Uses: the main raw materials to synthesize hormone and birth control drugs.
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Shaanxi Jiuyuan Biotechnology Co.,Ltd
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Yam is a yam plants. The main edible part of an underground tuber. Distribution of a wide range of yam, common in tropical and subtropical regions. Among Central and South America as the most, followed by subtropical region and Africa. The annual production of yam in the tropics is second only to cassava and sweet potato, but more than their nutritional value. It is the most important root crop, is one of the important food crops. |
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Pharma Sources Insight January 2025
