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Beijing Global Biologicals Co.Ltd
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Glutathione are thiol, and small molecule peptide. Glutathione is glutamic acid, cysteine and glycine combination of the three peptides, cysteine thiol on its active groups, glutathione has also prototype (G-SH) and oxidized type (GSSG) form, under physiological conditions to the majority of reduced glutathione, glutathione (GSH) is the main activity of the state, accounting for 95%; oxidized glutathione (GSSG) about 1% of the non-active state. Glutathione reductase catalyzing the interaction between the two types change. Coenzyme enzyme for the metabolism of sugar phosphates bypass provides NADPH.
Physical activity:
Glutathione has two important roles: anti-oxidation and the integration of detoxification. Glutathione, easy-to-iodine acetic acid, mustard gas (a gas), lead, mercury, arsenic and other heavy metal salt complex, but with the integration of detoxification. Glutathione (especially the liver cells of glutathione) has a very important physiological role is to integrate detoxification, with certain drugs (such as paracetamol), toxins (such as free radicals, heavy metals) and other integration, participation Biological transforming, thus bringing the body of harmful poisons into harmless substances, excreted from the body.
Application
(1) radiation sickness and radiation safety: radiation, radioactive substances or because of leukopenia caused by anticancer drugs and other symptoms can play a protective effect.
(2) to protect the liver, detoxification, inactivation of hormones, and to promote bile acid metabolism and help absorb fat and fat-soluble vitamins digestive tract.
(3) anti-allergy, or inflammation caused by hypoxemia in patients with systemic or local, can reduce cell damage and promote repair.
(4) to improve the course of certain diseases and symptoms as adjuvant drugs. Such as: hepatitis, hemolytic disease, and keratitis, cataract and retinal diseases, such as eye disease and improve vision.
(5) easy to speed up the metabolism of acids in the excretion of free radicals, which play a beauty skin care, anti-aging effect.
Shelf life and storage
24 months at normal temperature, drying and sealed conditions
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Changzhou Comwin Fine Chemicals Co., Ltd.
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L-Glutathione Reduced
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Chemical Name
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Glutathione
5-L-Glutamyl-L-cysteinylglycine;gamma-L-Glutamyl-L-cysteinylglycine; GSH
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CAS Number
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70-18-8
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Molecular Formula
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C10H17N3O6S
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Molecular Weight
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307.32
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Molecular Structure
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Packing
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25kg/Drum
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Capacity
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500tons/Year
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Storage
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Shading, sealed preservation.
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Application
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Widely used in medicines, nutritional health products, healthy functional foods, food supplements, whitening beauty products, cosmetics and so on. Commonly used dosage forms include freeze-dried powder injection, tablet, capsule, eye drops, etc.
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SPECIFICATION
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Specification |
| Appearance |
A white crystalline powder
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Identification(IR)
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Meets the requirements
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Identification(Optical Rotation)
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-15.5°~ -17.5°
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Inorganic Impurities
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Ammonium≤200ppm
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Arsenic≤2ppm
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Chlorides≤200ppm
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Sulphates≤300ppm
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Heavy Metals≤10ppm
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Iron≤10ppm
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Cadmium≤1ppm
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Lead≤3ppm
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M ercury≤1ppm
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Residue on Ignition≤0.10%
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Organic Impurities
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GSSG≤1.5%
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Total≤2.0%
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Clearity and Color of Solution
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Clear and Colorless
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Residual Solvents
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Meet the requirements
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Loss on Drying
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≤0.50%
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Microbiology
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Yeast and mold count≤100cfu/g
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| E. coli Absent/10g |
| S. aureus Absent/10g |
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Salmonella Absent/10G
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Total coliforms≤100cfu/g
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Total plate count≤1000cfu/g
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Assay (base on dry)
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98.0%~ 101.0%
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| Standard |
USP43 |
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Pharma Sources Insight June 2024: Globalization on the Go
