|
Glutathione is an antioxidant that helps protecting cells from reactive oxygen species such as free radicals and peroxides. By acting as an electron donor, glutathione reduces any disulfide bond formed within cytoplasmic proteins to cysteines. Glutathione is found almost exclusively in its reduced form, since the enzyme that reverts it from its oxidized form, glutathione reductase, is constitutively active and inducible upon oxidative stress. In fact, the ratio of reduced glutathione to oxidized glutathione within cells is often used scientifically as a measure of cellular toxicity.
| Product name |
L-Glutathione Reduced |
| Molecular Formula |
C20H32N6O12S2 |
| Molecular Weight |
612.63 |
| CAS No. |
70-18-8 |
| ENIECE No |
200-725-4 |
| Appearance |
white powder |
1. Food /cosmetic grade (≥98% , USP35 /USP37/USP41) ;
2.Pharmaceutical /injection grade ( ≥98% ,EP7) ;
L-Glutathione Reduced is widely used in Pharmaceuticals, Nutraceuticals,Health functional foods, Dietary supplements, Skin-Whitening products, Cosmetic etc
The regular dosage form: Lyophilized Powder for Injection,Tablets,Capsules, Eye drops etc.
| a. Daily nutraceuticals & Dietary supplement |
1. Anti-aging, antioxidant, maintain skin vigor and luster
2. Whitening skin: restraining the melanin
3. Improve immunity: enhance immune cells function effectively prevent viruses
| b. Drug treatment and prevention |
1. Protect liver: prevention & treatment of liver diseases
2. Detoxification: drugs and other kinds of poisoning auxiliary treatments,helpful for excreting toxins.
3. Prevention and treatment of eye diseases
4. Auxiliary treatment of diabetes
1. Technology from Japan, equipment from USA, EU and JANPAN, standard GMP workshop.
2. Fermentation process, using the non-GMO yeast, ensure product safety and high purity
3. Non-animal origin, Kosher, Halal and HACCP certificates.
4. Large capacity(200MT/year); have stock ;quick delivery time
5. We can provide GMP/DMF documents
| COA of L-Glutathione Reduced (USP41) |
|
Test Item
|
Specification
|
Result
|
Analytical Method Reference
|
|
Appearance
|
White or almost white crystalline powder
|
White crystalline powder
|
Visual
|
|
Appearance of solution
(10% w/v in water)
|
Clear and colorless
|
Complies
|
Visual
|
|
Bulk Density
|
≥0.50 g/ml
|
0.52 g/ml
|
In-house
|
|
Tapped Density
|
≥0.60 g/ml
|
0.65 g/ml
|
In-house
|
|
Particle Size
|
100% thru mesh 80
|
Complies
|
Mesh screen
|
|
Identification
|
S.O.R.
|
-15.5° ~ -17.5°
|
-16.0°
|
USP <781S>
|
|
Infrared
|
Positive
|
Positive
|
USP <197K>
|
|
Related
|
L-glutathione oxidized
|
≤1.5%
|
0.3%
|
Glutathione USP monograph
|
|
Total impurities
|
≤2.0%
|
1.5%
|
Glutathione USP monograph
|
|
Assay(dry basis)
|
98.0% to 101.0%
|
100.3%
|
Glutathione USP monograph
|
|
Loss on drying(3 h at 105℃)
|
≤0.5%
|
0.3%
|
USP <731>
|
|
Residue on Ignition
|
≤0.1%
|
<0.1%
|
USP <281>
|
|
Ammonium
|
≤200ppm
|
﹤200ppm
|
Glutathione USP monograph
|
|
Chloride
|
≤200ppm
|
﹤200ppm
|
USP <221>
|
|
Sulfate
|
≤300ppm
|
﹤300ppm
|
USP <221>
|
|
Iron
|
≤10ppm
|
﹤10ppm
|
USP <241>
|
|
Arsenic
|
≤1ppm
|
<1ppm
|
AFS
|
|
Cadmium
|
≤1ppm
|
<1ppm
|
AAS
|
|
Lead
|
≤1ppm
|
<1ppm
|
AAS
|
|
Mercury
|
≤1ppm
|
<1ppm
|
AFS
|
|
Heavy metals
|
≤10ppm
|
<10ppm
|
USP <231>Method I
|
|
Total Plate Count
|
≤1000 cfu/g
|
<10 cfu/g
|
USP <61>
|
|
Yeast and Mold
|
≤100 cfu/g
|
25 cfu/g
|
USP <61>
|
|
Coliforms
|
≤30 cfu/g
|
<10 cfu/g
|
USP <61>
|
|
E. Coli
|
Negative/g
|
Negative
|
USP <62>
|
|
Salmonella
|
Negative/10g
|
Negative
|
USP <62>
|
|
Staphylococcus Aureus
|
Negative/g
|
Negative
|
USP <62>
|
|
Conclusion: Complies with the USP 41 standards.
|
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Pharma Sources Insight June 2024: Globalization on the Go
