|
Shandong Sihuan Pharmaceutical Co.,Ltd.
|
Product Name: (R)-3-Piperidinamine dihydrochloride
Synonyms: R-3-AMnio piperidine dihydrochloride;(R)-PIPERIDIN-3-YLAMINE DIHYDROCHLORIDE;(R)-PIPERIDINE-3-AMINE DIHYDROCHLORIDE;(R)-(-)-3-AMINOPIPERIDINE DIHYDROCHLORIDE;(R)-3-AMINOPIPERIDINE DIHYDROCHLORIDE;(R)-3-PIPERIDINAMINE DIHYDROCHLORIDE;R-3-AMINOPIPERIDINE DIHCL;Linagliptin interMediate D
CAS: 334618-23-4
MF: C5H14Cl2N2
MW: 173.08406
EINECS: 608-870-9 |
Send Inquiry
|
|
Sinoway Industrial Co. Ltd
|
|
Product name
|
(R)-3-Piperidinamine dihydrochloride;
Alogliptin intermediate
|
|
CAS No.
|
334618-23-4
|
|
Molecular Formula
|
C5H14Cl2N2
|
|
Molecular Weight
|
136.625
|
|
Molecular Structure
|
 |
|
Quality Standard
|
99% up by HPLC
|
|
Appearance
|
White or off-white powder
|
|
ANALYSIS
|
SPECIFICATION
|
RESULTS
|
|
Appearance
|
White or off-white powder
|
White powder
|
|
Identification
|
NMR：The HNMR spectrum conforms to structure
|
Conforms
|
|
IR：The IR spectrum conforms to reference substance
|
Conforms
|
|
Purity by GC
Each single impurity
|
> 99.0%
< 0.2%
|
99.6%
0.1% (Max)
|
|
Purity by HPLC
Each single impurity
|
> 99.0%
< 0.2%
|
99.9%
0.1%
|
|
e e by HPLC(derivative)
|
> 99.2%
|
100.0%
|
|
Water content by KF
|
< 0.5%
|
0.06%
|
|
Loss on drying
|
< 0.5%
|
0.2%
|
|
Residue on ignition
|
< 0.3%
|
0.07%
|
|
Specific optical rotation
|
-2士1° (C=4, H20)
|
[α]D/20=-1.9°
|
|
Heavy metals
- Pd
- Ni
|
< 20 ppm
< 10 ppm
|
< 20 ppm
< 10 ppm
|
|
Conclusion
|
The product meets specification
|
What is (R)-3-Piperidinamine dihydrochloride?
(R)-3-Piperidinamine dihydrochloride is one of key intermediates of Alogliptin (API). Alogliptin is used together with proper diet and exercise to treat high blood sugar levels caused by type 2 diabetes. Alogliptin helps to control blood sugar levels by increasing substances in the body that make the pancreas release more insulin.
|
Send Inquiry
|
Pharma Sources Insight January 2025
