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Shandong Binzhou Zhiyuan Biotechnology Co., Ltd.
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Manufacturer Of Sulfobutyl Ether-beta-cyclodextrin Sodium Salt Manufacturers, Suppliers, Factory and Company - Zhiyuan Biological Name: sulfobutyl ether-beta-cyclodextrin sodium salt DMF NO.: 030167 Other name : betadex sulfobutyl ether sodium ; sulfobutyl ether-β-cyclodextrin sodium salt CAS: 182410-00-0 Abbreviation: SBEBCD Molecular formula : C42H70-nO35 (C4H8O3S Na)n Molecular weight: 1135+158n Qaulity ： injection grade / oral grade Standard : USP Package: 500g/bag , 1kg/bag , 2kg/bag, 10kg/drum , 20kg/drum Use : medical Features and applications: SBE-β-CD is a high water-soluble anionic cyclodextrin derivative. It can easily form non-covalent inclusion complexes with drug molecules, thus it has the good performances in enhancing drug stability, solubility and safety, reducing drug toxicity and hemolysis, covering up bad smell, and controlling drug release rate.
SBE-β-CD has been used in injection, oral, nasal and eye medication. Modification by charged functional units can improve the binding affinity of cyclodextrins for oppositely charged guests, so it has a special affinity for drugs with nitrogen elements. |
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Shandong Binzhou Zhiyuan Biotechnology Co., Ltd.
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Sertraline is selective serotonin recycle inhibitor (SSRI), the latest in a can help to improve the ability of the body, effectively alleviate the patient's depressive symptoms, including irritable mood, and can reduce the fatigue and anxiety state of sustainability, has a long-term, low poisonous to the cells of liver, the body clear, very suitable for the elderly taking etc., in the world has been widely used to treat depressive and obsessive-compulsive disorder.Compared with sertraline hydrochloride tablets, the oral liquid containing sertraline hydrochloride has the advantages of convenient taking, stable storage at low or normal temperature, fast absorption, good taste, more suitable for elderly patients, simple process and material saving.The present invention solves the sertraline hydrochloride oral liquid preparation technology on the key problem of solubility and stability problems, choose in the use of doses non-toxic excitant hydroxypropyl times he almost cyclodextrins and sugar mixture of lauric acid ester as solubilizer and stabilizer, which provides a with hydroxypropyl times he cyclodextrins and sugar mixture of lauric acid ester as solubilizer and stabilizer of sertraline hydrochloride oral solution. Shandong binzhou wisdom source biological technology co., LTD., is committed to specializing in the production of pharmaceutical excipients hydroxypropyl times he cyclodextrins and sodium sulfonated butyl times he cyclodextrin, has standard GMP management, advanced production equipment, professional team of experts, the sale of our products at the same time, also widely used in food, cosmetics, scientific research and other fields, you just need to, we just professional, welcome from all walks of life to come to visit.
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Shandong Binzhou Zhiyuan Biotechnology Co., Ltd.
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Name: Hydroxypropyl Betadex
Other Name : 2-hydroxypropyl-beta-cyclodextirn ;
Hydroxypropyl-β-cyclodextrin.
Abbreviation : HPBCD
CAS: 128446-35-5
EINECS: 420-920-1
Molecular formula : C42H70-nO35(C3H8O2)n
Molecular weight: 1134.98+58n
Solubility (in 100cm3 solvent, at 25℃) : Water: >180g
Methanol: >33g
DMSO: >33g
Qaulity ：Pharma grade
Standard : USP42/ EP9.6
Package: 500g/bag , 2kg/bag, 10kg/drum
Use : Medical field
Applications In pharmaceuticals industry:
Hydroxypropyl Betadex can increase solubility and bioavailability of insoluble drugs, so that the efficacy of drugs can last longer with less ingestion of drugs. It can adjust and control drugs release ratio, decrease side effects of drugs, and enhance stability of drugs. HP-β-CD can be used for oral medication, injection, mucosal delivery systems (including the nasal mucosa, rectum, cornea, etc.), dermal drug delivery systems, lipophilic drugs targeting delivery, and also used as protective agent and stabilizer of protein.
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Pharma Sources Insight June 2024: Globalization on the Go
