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Home > CAS No. Inquiry > 182410-00-0

182410-00-0

[CAS Name] .beta.-Cyclodextrin, sulfobutyl ethers, sodium salts

[Formula]

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Basica Info

[CAS Name].beta.-Cyclodextrin, sulfobutyl ethers, sodium salts
[Alias].beta.-Cyclodextrin, sulfobutyl ethers, sodium salts;CAPTISOL;Sodium sulfobutylether β-cyclodextrin;Betadex Sulfobutyl Ether Sodium (500 mg)
[Number]182410-00-0
[EINECS]
[Formula]
[Molecular weight]

182410-00-0 Suppliers

Company

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Shandong Binzhou Zhiyuan Biotechnology Co., Ltd

Basic information

Name: Betadex sulfobutyl ether sodium

CAS: 182410-00-0

Molecular formula :C₄₂H_70-nO₃₅ (C₄H₈O₃S Na)n

Molecular weight: 1135+158n

Qaulity : Injection grade

Standard : USP41

Package: 500g/bag , 1kg/bag, 10kg/drum , 20kg/drum or customized

The role in ophthalmic medicine

Betadex sulfobutyl ether sodium has little stimulation on cornea and can reduce the irritation of drugs on the eyeball, so it is very suitable for the preparation of eye drops with physiological pH and osmotic pressure requirements.

Ganciclovir was soluble in water, but the water solubility was significantly affected by pH, more easily in dissolved under acidic conditions. The pH and osmotic pressure of the eyedrops are strictly required. The results showed that the Betadex sulfobutyl ether sodium in the prescription significantly reduced the eye irritation of ganciclovir, and the inclusion of Betadex sulfobutyl ether sodium on the drug could increase the biocompatibility of the eye drops.

O,O’-Dipropionyl-(1,4-xylylene)bispilocarpate is a precursor of trabeculin, a drug for glaucoma treatment. It has a strong irritation to the eye and affects its clinical application. After adding Betadex sulfobutyl ether sodium to the prescription of the eye drops, it was found that the irritation of Betadex sulfobutyl ether sodium eye drops to rabbit eyes was significantly reduced within the range of 24 ~ 36mmol. L-1. The mechanism may be that when the drug forms a inclusion compound with Betadex sulfobutyl ether sodium, the inclusion compound can slowly release the drug in the eye, so as to reduce the local concentration of the free drug and reduce or eliminate the eye irritation caused by the rapid absorption or precipitation of the drug.

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Shandong Binzhou Zhiyuan Biotechnology Co., Ltd

Product Categories

Native Cyclodextrin
Medicinals Cyclodextrin
Cyclodextrin Derivatives
Cyclodextrin Complexes
Cyclodextrin Polymers

Shandong Binzhou Zhiyuan Biotechnology Co.,Ltd

Tel: +86-543-2616568

Fax: +86-543-2605568

Email: info@cydextrin.com

Add: Boxing Economic Development Zone, Binzhou, Shandong, China

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Manufacturer Of Sulfobutyl Ether-Beta-Cyclodextrin Sodium Salt

Manufacturer Of Sulfobutyl Ether-beta-cyclodextrin Sodium Salt

Name: sulfobutyl ether-beta-cyclodextrin sodium salt DMF NO.: 030167 Other name : betadex sulfobutyl ether sodium ; sulfobutyl ether- β -cyclodextrin sodium salt CAS: 182410-00-0 Abbreviation: SBEBCD Molecular formula : C 42 H 70-n O 35 (C 4 H 8 O 3 S Na)n Molecular weight: 1135+158n Qaulity ：...

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FeaturesProduct Details

Name: sulfobutyl ether-beta-cyclodextrin sodium salt

DMF NO.: 030167

Other name : betadex sulfobutyl ether sodium ; sulfobutyl ether-β-cyclodextrin sodium salt

CAS: 182410-00-0

Abbreviation: SBEBCD

Molecular formula : C₄₂H_70-nO₃₅ (C₄H₈O₃S Na)n

Molecular weight: 1135+158n

Qaulity ： injection grade / oral grade

Standard : USP40 / EP9.0

Package: 500g/bag , 1kg/bag , 2kg/bag, 10kg/drum , 20kg/drum

Use : medical

Features and applications:

SBE-β-CD is a high water-soluble anionic cyclodextrin derivative. It can easily form non-covalent inclusion complexes with drug molecules, thus it has the good performances in enhancing drug stability, solubility and safety, reducing drug toxicity and hemolysis, covering up bad smell, and controlling drug release rate.
SBE-β-CD has been used in injection, oral, nasal and eye medication. Modification by charged functional units can improve the binding affinity of cyclodextrins for oppositely charged guests, so it has a special affinity for drugs with nitrogen elements.

If you're looking for the high-quality manufacturer of sulfobutyl ether-beta-cyclodextrin sodium salt, our company must be your best choice. We're one of the leading manufacturers and supplier with rich experience and wide expertise. Please be rest assured to buy the products from our factory.

Hot Tags: manufacturer of sulfobutyl ether-beta-cyclodextrin sodium salt, manufacturers, suppliers, factory, company, buy, high-quality

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Shandong Binzhou Zhiyuan Biotechnology Co., Ltd

Name: sulfobutyl ether-beta-cyclodextrin sodium salt

DMF NO.: 030167

Other name : betadex sulfobutyl ether sodium ; sulfobutyl ether-β-cyclodextrin sodium salt

CAS: 182410-00-0

Abbreviation: SBEBCD

Molecular formula : C42H70-nO35 (C4H8O3S Na)n

Molecular weight: 1135+158n

Qaulity ： injection grade / oral grade

Standard : USP

Package: 500g/bag , 1kg/bag , 2kg/bag, 10kg/drum , 20kg/drum

Use : medical

Features and applications:

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