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Sinoway Industrial Co.Ltd.
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Product name
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Ropivacaine Hydrochloride / Ropivacaine HCL
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CAS No.
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132112-35-7
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Molecular Formula
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C17H26N2O·HCl·
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Molecular Weight
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328.88
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Quality Standard
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98% up by HPLC
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Appearance
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White powder
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COA of Ropivacaine Hydrochloride
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Items
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Specifications
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Results
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Appearance
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White Powder
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Complies
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Assay (HPLC)
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98%min
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99.8%
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Odor
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Characteristic
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Complies
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Sieve analysis
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100% pass 80 mesh
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Complies
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Heavy Metal
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<10ppm
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Complies
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As
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< 0.1ppm
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0.05ppm
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Pb
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< 0.1ppm
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0.05ppm
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Cd
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< 0.1ppm
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0.05ppm
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Residual solvents
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<100ppm
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Complies
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Residual pesticide
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Negative
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Complies
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Total Plate Count
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< 1000 cfu/g
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Complies
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Yeast&Mold
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< 100 cfu/g
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Complies
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E.Coli
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Negative
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Complies
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Salmonella
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Negative
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Complies
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Conclusion
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Meet the specification of standards
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Function of Ropivacaine Hydrochloride
Since it was discovered that long-acting local anesthetics can induce cardiac arrest, people have been seeking alternative medicines that are less fat-soluble and safer. Ropivacaine is such a new type of long-acting amide local anesthetic, which has a long duration of action, and has anesthetic and analgesic effects. Its pharmacological characteristics are low cardiotoxicity, obvious separation of sensory block and motor block, and peripheral vasoconstriction. Therefore, the drug is especially suitable for postoperative analgesia and obstetric anesthesia.
Compared with traditional local anesthetics, Ropivacaine HCL has the following advantages:
1. Curative effect: The action time of ropivacaine is significantly longer than other long-acting local anesthetics, and the action time of subcutaneous infiltration anesthesia is 2 to 3 times longer than that of bupivacaine of the same concentration.
2. Unique curative effect-the sensory-motor block separation of ropivacaine is much greater than that of bupivacaine, and the clearance rate is higher, making it more suitable for analgesia.
3. Strong controllability-the anesthetic effect of ropivacaine is dose-dependent, which means that the degree of sensory and motor block produced by ropivacaine is predictable and controllable.
4. Low toxic and side effects-Ropivacaine does not have the disadvantage of greater cardiotoxicity of general long-acting local anesthetics. Cardiotoxicity is rarely caused by this product, and the fetus has good tolerance to this product.
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