Cas no for 128446-35-5,(2-HYDROXYPROPYL)-BETA-CYCLODEXTRIN ACID Cas number search msds database,online free cas number chemistry search engine,cas number sigma aldrich

Products
Suppliers
Sourcing Requests

Post Sourcing Request Exhibition

Home
Products
Supplier
E-Trade Season
Content Hub
Industry Insights
Service & Membership
For Supplier

My Account

My Online Store

My EZSourcing

View Sourcing Requests

Customer Service
For Buyer

Search Products & Suppliers
Products Directory Suppliers Discovery Post EZSourcing
Service
Buyer Sourcing Event Contact Us
Quick links
My Favorites Recent Visit History

Home > CAS No. Inquiry > 128446-35-5

128446-35-5

[CAS Name] (2-HYDROXYPROPYL)-BETA-CYCLODEXTRIN

[Formula] C63H112O42

Search Products Post Sourcing Request

Basica Info

[CAS Name](2-HYDROXYPROPYL)-BETA-CYCLODEXTRIN
[Alias]beta-cyclodextrin,2-hydroxypropylether;beta-hydroxypropylcyclodextrin;(2-HYDROXYPROPYL)-BETA-CYCLODEXTRIN;(2-Hydroxypropyl)-β-cyclodextrin;2-Hydroxypropyl-B-Cyclodextrin;2-HYDROXYPROPYL-B-CYCLODEXTRIN CELLCULTU RE TESTED;HYDROXYPROPYL-BETA-CYCLODEXTRIN (MS = 0. 8);(2-HYDROXYPROPYL)-BETA-CYCLODEXTRIN (MS=1.0)
[Number]128446-35-5
[EINECS]420-920-1
[Formula]C63H112O42
[Molecular weight]1541.54

[Melting point]278 °C (dec.)

128446-35-5 Suppliers

Company

Main Products

Shandong Binzhou Zhiyuan Biotechnology Co., Ltd.

Cyclodextrins are a family of compounds made up of sugar molecules bound together in a ring. Cyclodextrins are produced from starch by means of enzymatic conversion. They are used in food, pharmaceutical, drug delivery, and chemical industries, as well as agriculture and environmental engineering. Hydroxypropyl Beta Cyclodextrin is the chief active compound found in Procter and Gamble's deodorizing product "Febreze" under the brand name "Clenzaire".

Hydroxypropyl Beta Cyclodextrin is a prime candidate of all the chemically modified Cyclodextrins for incorporation into formulations used by humans and animals. HPBCD has the best balance of enhanced aqueous solubility, a wide range of drugs with which it forms stable complexes, and the most extensive collection of safety data in the technical literature with no adverse reactions reported. HPBCD is itself very soluble in water.

Basically used in solution to facilitate drug delivery.

ITEMS		criteria
Appearance		White or almost white, amorphous or crystalline powder. Freely soluble in water and in propylene glycol.
Identification	IR	Same absorption bands as USP Hydroxypropyl Betadex RS
	Clarity of Solution	Positive
Molar Substitution		0.40~1.50
Betadex		≤1.5%
Propylene Glycol		≤2.5%
Any Other Single Impurity		≤0.25%
Total Impurities Excluding Betadex and Propylene Glycol		≤1.0%
Propylene Oxide		≤0.0001%
Loss on Drying		≤10.0%
Clarity of Solution		1.0g/2ml water solution is clear and transparent
Conductivity		≤200µS/cm
The total aerobic microbial count		≤1000cfu/g
The total combined moulds and yeasts count		≤100cfu/g

If you're looking for the high-quality hydroxypropyl-beta-cyclodextrin cas 128446-35-5, our company must be your best choice. We're one of the leading manufacturers and supplier with rich experience and wide expertise. Please be rest assured to buy the products from our factory.

Send Inquiry

Shandong Binzhou Zhiyuan Biotechnology Co., Ltd.

Daily chemical grade Methyl-Beta-Cyclodextrin CAS NO 128446-36-6

001

Product Introduction

Methyl-beta-cyclodextrin can reduce microbial contamination and skin irritations, keep skin moist, mask bad odors, promote transdermal absorption of activeingredients in cosmetic.

Methyl Beta Cyclodextrin can decrease the stimulating effect on the skin produced by organic composition of cosmetic.

Methyl Beta Cyclodextrin can prevent nutrient ingredient evaporating and oxidating

Basic information of the Methyl-Beta-Cyclodextrin

Product Name : Methyl Beta Cyclodextrin

......................................................................................................................................................

CAS NO. : 128446-36-6

......................................................................................................................................................

Molecular Formula : C42H70-nO35 · (CH3)n

......................................................................................................................................................

Molecular Weight : 1135 + n•(14.0)

......................................................................................................................................................

Molecular structuer:

002

Product Specification

Methyl-Beta-Cyclodextrin
Test Standard	Enterprise standard
ITEMS	SPECIFICATION
Appearance	White or almost white powder;Odorless, slightly sweet;Freely soluble in water，soluble in methanol and ethanol.
Assay	≥98％
Specific rotation	+154°～+165°
Water solution pH	pH5.0～7.5
Light-absorbing impurities	Between 230 nm and 350 nm,the absorbance is not greater than 1.0; and between 350 nm and 750 nm, the absorbance is not greater than 0.1
Average Degree of Substitution	7.0～13.3
Loss on Drying	≤7.0％
Beta cyclodextrin	≤0.2％
Residue on Ignition	≤0.5％
Heavy Metal	≤10ppm
Sulfate	≤0.2％
Chloride	≤0.2％
The total aerobic microbial coun	≤1000
The total combined moulds and yeasts count	≤100
Escherichia coli	Absent
Packaging and storage	Preserve in well-closed containers.

Packing & Shipping

Packing Detail:10kg/bag/drum

Delivery & Payment

Payment : T/T in advance

Delivery : Delivery goods immediately after receipt the payment.

Product description:
In the fields of food and spice

Methyl-beta-cyclodextrin can improve the stability and long effect of nutritional elements also it can cover up and correct the ordor and taste of food nutrition elements.

Quick Details

CAS No.:128446-36-6

Other Names:Methyl-beta-cyclodextrin

MF: C56H98O35

Place of Origin:Shandong, China

Type:Antibiotic and Antimicrobial Agents

Grade Standard:Medicine Grade

Usage:Animal Pharmaceuticals

Brand Name: Zhiyuan

Model Number:Methyl-beta-cyclodextrin

Purity:99%min

Product Name:Methyl-beta-cyclodextrin

Molecular Weight:1331.3563

Vapour Pressur:0mmHg at 25°C

Density:1.4g/cm3

Melting point:180-182℃

Boiling point:1203.6°C at 760 mmHg

Refractive index:1.552

Flash point:681.7°C

Methyl-beta-cyclodextrin Appearance:White Powder

Shelf life:24 Months

Supply Ability

Supply Ability:8000 Kilogram/Kilograms per Month

Packaging & Delivery

Packaging Details: 10kg/drum,1kg/bag

Port: qingdao port

High qulity Methyl-beta-cyclodextrine 98%min CAS No.:128446-36-6

1.Competitive price
2.Fast Delivery Within 2 days
3.SGS , BV, GMP,ISO approve
4.Professional factory

Application of Methyl-beta-cyclodextrin

1 In Medical field, it can promotes the dissolusion efficiency of the drugs, enhancing bioavailability and solubility of drugs,so that to reduce the dose but increase the efficacy, mainly used in medicine of oral liquid.

2 In the fields of food and spice, I can improve the stability of nutritions molecular and keep it for long-term effective, and it can masks and correctes the bad smell and tastes in foods nutrition molecular.

3.In cosmetics field,it can reduce the stimulation from organic molecules to the skin,strengthen the stability of the materials and to prevent volatiled and oxidated of nutrient compositions

Send Inquiry

Shandong Binzhou Zhiyuan Biotechnology Co., Ltd.

Description

(2-Hydroxypropyl)-β-cyclodextrin is a widely used drug delivery vehicle to improve the stability and bioavailability.

In Vitro

Cell treatment with (2-Hydroxypropyl)-β-cyclodextrin results in the activation of the transcription factor EB, a master regulator of lysosomal function and autophagy, and in enhancement of the cellular autophagic clearance capacity[1]. (2-Hydroxypropyl)-β-cyclodextrin treatment reduces intracellular cholesterol resulting in significant leukemic cell growth inhibition through G2/M cell-cycle arrest and apoptosis. The IC50 values for (2-Hydroxypropyl)-β-cyclodextrin after 72 hours exposure are in the range of 3.86–10.09 mM. (2-Hydroxypropyl)-β-cyclodextrin also shows anticancer effects against CML cells expressing a T315I BCR-ABL mutation (that confers resistance to most ABL tyrosine kinase inhibitors), and hypoxia-adapted CML cells that have characteristics of leukemic stem cells. In addition, colony forming ability of human primary AML and CML cells is inhibited by (2-Hydroxypropyl)-β-cyclodextrin.

In Vivo

(2-Hydroxypropyl)-β-cyclodextrin administration promotes transcription factor EB-mediated clearance of proteolipid aggregates that accumulate due to inefficient activity of the lysosome-autophagy system in cells derived from a patient with a lysosomal storage disorder. Intraperitoneal injection of (2-Hydroxypropyl)-β-cyclodextrin significantly improves survival in leukemia mouse models. Systemic administration of (2-Hydroxypropyl)-β-cyclodextrin to mice has no significant adverse effects.

Send Inquiry

Previous page 1 2 3 4 5 6 7 8 9 10 ... 13 14 Next page

PharmaSources@imsinoexpo.com

Tel: (+86) 400 610 1188

WhatsApp/Telegram/Wechat: +86 13621645194

About Us: About PharmaSources; Terms of Service; Privacy Policy; Intellectual Property; Media Partners

Buy: Search Products; Post Sourcing Requests; Search Suppliers; CAS Search

Sell: Member Application; Advertising; Post Products; EZSourcing

Events: CPHI China; PMEC China; Conferences; Search Events

Help: FAQ; Contact Us; Feedback

Links：
CCCMHPIE SJGLE.com JJGLE.COM JDGLE.COM XIUGLE.COM DENGGLE.COM HPGLE.COM
Follow Us：
Pharma Sources Insight June 2024: Globalization on the Go

PharmaSources Customer Service