Cas no for 128446-35-5,(2-HYDROXYPROPYL)-BETA-CYCLODEXTRIN ACID Cas number search msds database,online free cas number chemistry search engine,cas number sigma aldrich

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Home > CAS No. Inquiry > 128446-35-5

128446-35-5

[CAS Name] (2-HYDROXYPROPYL)-BETA-CYCLODEXTRIN

[Formula] C63H112O42

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Basica Info

[CAS Name](2-HYDROXYPROPYL)-BETA-CYCLODEXTRIN
[Alias]beta-cyclodextrin,2-hydroxypropylether;beta-hydroxypropylcyclodextrin;(2-HYDROXYPROPYL)-BETA-CYCLODEXTRIN;(2-Hydroxypropyl)-β-cyclodextrin;2-Hydroxypropyl-B-Cyclodextrin;2-HYDROXYPROPYL-B-CYCLODEXTRIN CELLCULTU RE TESTED;HYDROXYPROPYL-BETA-CYCLODEXTRIN (MS = 0. 8);(2-HYDROXYPROPYL)-BETA-CYCLODEXTRIN (MS=1.0)
[Number]128446-35-5
[EINECS]420-920-1
[Formula]C63H112O42
[Molecular weight]1541.54

[Melting point]278 °C (dec.)

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Shandong Binzhou Zhiyuan Biotechnology Co., Ltd.

Hydroxypropyl Betadex Oral pharma grade USP Standard

Product name: Hydroxypropyl Betadex

CAS No.:128446-35-5

DMF No.:030168

Standard :CP / USP /EP

Grade: Oral grade / Pharma grade

Basic information of the oral grade Hydroxypropyl Betadex

Product Name: Hydroxypropyl Betadex oral grade

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Synonyms: Hydroxypropyl-β-Cyclodextrin; Hydroxypropyl beta Cyclodextrin

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Molecular Formula: C42H70-nO35(C3H8O2)n

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Molecular Weight: 1134.98+58n

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Molecular structure:

Product Specification

Test Standard	USP
ITEMS	SPECIFICATION
Molar Substitution	0.40-1.50
Clarity of solution	50%(w/v) water solution is clear
Identification(IR)	same absorption bands as USP Hydroxypropyl Betadex RS
Loss on Drying	≤10.0％
Conductivity	10%(w/v) water solution ≤200µS/cm
Propylene oxide	≤1ppm
Propylene glycol	≤2.5％
Sum of Other Impurities	≤1％
Betadex	≤1.5%
Any other single impurity	≤0.25％
TAMC(cfu/g)	≤1000cfu/g
TYMC(cfu/g)	≤100cfu/g

Main usage of Hydroxypropyl Betadex Oral pharma grade

To increase the solubility of medicine and biological availability
To improve the bioavailability of drugs.
To adjust or control the releasing of drugs.
To decrease the toxicities of drugs.
To improve the stabilities of drugs.

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Shandong Binzhou Zhiyuan Biotechnology Co., Ltd.

[technical hydroxypropyl betacyclodextrin] basic information:

Product Name: technical grade hydroxypropyl betacyclodextrin

Quality: enterprise standard

Appearance shape: white powder

CAS NO.： 128446-35-5

Molecular formula: c42h70-no35 (c3h7o) n

Molecular weight: 1134.98 + 58n

[technical hydroxypropyl betacyclodextrin] main advantages:

·Factory direct sales, spot supply, has a strong supply capacity, the existing technical grade hydroxypropyl betacyclodextrin annual capacity of 1000 tons.

Due to the special molecular structure of hydroxypropyl cyclodextrin, the application area of this product has been expanding. Besides the use of drugs, it has been widely used in veterinary medicine, food, cosmetics, flavors and fragrances and other chemical fields. Shandong Binzhou Zhiyuan Biotechnology Co., Ltd. has developed hydroxypropyl betacyclodextrin products with different quality requirements according to the use characteristics.

·Documents: professional domestic and foreign trade personnel, familiar with the operation process, timely provide the required documents.

·Have long-term cooperation of professional logistics and express, ensure the safety of transportation and timely delivery.

·Pre sales and after-sales service: timely answer customer's questions before sales and provide technical support after sales.

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Shandong Binzhou Zhiyuan Biotechnology Co., Ltd.

Hydroxyproplyl Beta Cyclodextrin (hydroxypropyl betadex) are purified polydisperse products resulting from the controlled reaction of propylene oxide and native beta-cyclodextrin. Hydroxypropyl beta-cyclodextrin is itself very soluble in water (greater than 500 mg/ml at room temperature compared to 18 mg/ml for beta-cyclodextrin), and is used for molecular encapsulation of a variety of sparingly water compounds to enhance the aqueous solubility of the encapsulated compound.

Other Name: Hydroxyproplyl Beta Cyclodextrin

CAS No.: 128446-35-5

Molecular Structure:

Standards: USP,CP2020

Grade: Oral or Injection

Storage:Preserved in well-closed containers

Shelf life : 2 years when properly stored.

Package:10kg/drum,20kg/drum.

Medical use of hydroxypropyl beta cyclodextrin

Hydroxypropyl beta cyclodextrin is considered an ideal pharmaceutical excipient and solubilizer in injections in pharmaceutical industry.Due to the low surface activity, low hemolytic activity and non-irritation to muscles.

Hydroxypropyl beta cyclodextrin works to solubilize water-insoluble drugs, enhance drug stability, improve drug bio-availability (improve efficacy or lower dosage of drugs), moderate and control drug release, and can also help to diminish the toxicity and side effects of drugs.

Further, hydroxypropyl beta cyclodextrin can be applied as a drug carrier in oral medications, injections, mucosal drug delivery system, transdermal drug delivery system, and targeted lipophilic drugs. Also, it is suitable as a protectant and stabilizer for proteins.

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