What is Tranexamic Acid?
Tranexamic Acid(CAS No.1197-18-8) is a synthetic derivative of the amino acid lysine, known for its antifibrinolytic properties. This potent medication is carefully formulated to prevent the breakdown of blood clots, ensuring hemostasis and reducing the risk of bleeding complications. Tranexamic Acid is available in various forms, including intravenous injections and oral tablets.
How Does Tranexamic Acid Work?
Tranexamic Acid works by blocking the action of plasmin, an enzyme responsible for breaking down blood clots. By inhibiting plasmin, the medication helps stabilize blood clots and prevents their premature dissolution. This essential mechanism allows Tranexamic Acid to control bleeding effectively, making it a valuable asset in various medical scenarios.
Key Features and Benefits:
1:Surgical Hemostasis: Tranexamic Acid is extensively used in surgeries to minimize blood loss and reduce the need for blood transfusions, promoting better patient outcomes.
2:Trauma Management: In cases of trauma or injury, Tranexamic Acid plays a critical role in preventing excessive bleeding and supporting emergency medical care.
3:Menstrual Bleeding: For women with heavy menstrual bleeding, Tranexamic Acid offers relief by reducing blood loss and menstrual discomfort.
4:Dental Procedures: Tranexamic Acid is utilized in oral surgery and dental procedures to control bleeding and facilitate proper wound healing.
5:Hemophilia and Bleeding Disorders: Tranexamic Acid is a valuable adjunct in the management of bleeding disorders like hemophilia, supporting overall patient care.
|
Product Name
|
Tranexamic acid
|
Drums Sampled & Sample Qty.
|
7/Drums 30g
|
|
Batch No.
|
X2112308M
|
Date Sample Received
|
2022.05.19
|
|
Drums/Qty.
|
700.0Kg 28/Drums
|
COA Issuing Date
|
2022.05.24
|
|
Test Items
|
All items
|
Mfg. Date
|
2021.12.02
|
|
Quality Specification
|
ZLBZ/K012-29&EP9.0/BP2018
|
Retest Date
|
2026.12.01
|
|
Items of Test
|
Customer's Requirements
|
Test Result
|
|
CHARACTERS
|
Appearance: White or almost white, crystalline powder
|
White crystalline powder
|
|
Solubility: Freely soluble in water and in glacial acetic acid, practically insoluble in acetone and in ethanol (96%)
|
Pass
|
|
IDENTIFICATION
|
Infrared Absorption Spectrophotometry: IR spectrum is in concordance with Tranexamic acid CRS
|
Pass
|
|
|
pH(2.2.3)
|
7.0 ～ 8.0
|
7.4
|
|
(HPLC 2.2.29)
Related
Substances
(HPLC2.2.29
|
Impurity A≤0.1%
|
Not Detected
|
|
Impurity B<0.2%
|
0.04%
|
|
Unspecified impurities≤0.10%
|
lmpurity C
Impurity D
Other Impurities
|
0.003%
0.001%
Not Detected
|
|
Sum of unspecified impurities≤ 0.2%
|
0.004%
|
|
Halides Expressed
as Chlorides
|
≤140ppm
|
<140ppm
|
|
Loss on Drying
|
≤0.5%
|
0.034%
|
|
Sulphated Ash
|
≤0.1%
|
0.029%
|
|
ASSAY
(Titration 2.2.20)
|
Should be within(Dried based) 99.0%～101.0%
|
100.1%
|
|
Pharma Sources Insight June 2024: Globalization on the Go
