FUJIAN COMHONY BIOTECHNOLOGY CO., LTD
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Mupirocin is used as a topical treatment for bacterial skin infections, for example, furuncle, impetigo, open wounds, etc. It is also useful in the treatment of superficial methicillin-resistant Staphylococcus aureus (MRSA) infections. |
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Hebei Shengmei Medical Technology Co.,Ltd.
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Mupirocin is a topical antibiotic useful against superficial skin infections such as impetigo or folliculitis. It may also be used to get rid of methicillin-resistant S. aureus (MRSA) when present in the nose without symptoms. Due to concerns of developing resistance, use for greater than ten days is not recommended. It is used as a cream or ointment applied to the skin. |
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Sinoway Industrial Co.Ltd.
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Product name
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Mupirocin
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Molecular Formula
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C26H44O9
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Molecular Weight
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500.6222
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CAS No.
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12650-69-0
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Quality Standard
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GMP / USP34 / EP6
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Appearance
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white powder
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ITEMS
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SPECIFICATIONS
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RESULT
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Appearance
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A white or off-white powder
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Conforms
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Identification(A,B)
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Positive
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Conforms
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Specific Optical Rotation
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-20°~ -16°
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-18°
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Impurity C
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Not more than 2.5%
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1.6%
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Individual impurity
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Not more than 1.0%
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Conforms
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Total impurities
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Not more than 4.5%
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3.5%
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Chlorides
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Not more than 0.5%
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Conforms
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PH
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3.0~4.5
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3.6
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Water
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Not more than 1.0%
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0.1%
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Residual Solvents
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Ethyl Acetate
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Not more than 500 ppm
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Not deteced
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Isobutyl Acetate
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Not more than 5000 ppm
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5
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Heptane
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Not more than 500 ppm
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2
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Acetone
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Not more than 3000 ppm
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15
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Assay
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93.0-102.0%
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98.1%
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Mupirocin is a topical antibiotic for external use, which is a substance produced by Pseudomonas fluorescens culture fluid, namely Pseudomonas A. Its antibacterial effect is mainly by reversibly combining with isoleucine transfer RNA synthetase, preventing isoleucine infiltration, and stopping the synthesis of isoleucine-containing protein in cells to play a bactericidal or bacteriostatic role. Mupirocinshows bacteriostatic effect at very low concentration and bactericidal effect at high concentration. Mupirocin is highly sensitive to various Gram-positive cocci related to skin infections, especially Staphylococcus and Streptococcus. It is also effective against resistant Staphylococcus aureus; Neisseria gonorrhoeae has some antibacterial effect; it is not sensitive to most anaerobic bacteria and normal skin flora. The incidence of drug-resistant mutants in vitro is very low.
We are professional mupirocin manufacturer and we have mupirocin for sale including mupirocin for acne, mupirocin for ringworm and mupirocin for eczema.
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